Synonyms: Acadesine; Aminoimidazole carboxamide ribonucleotide; AICA ribonucleotide; ZMP; 5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide. 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide CAS ID: 2627-69-2 Molecular Formula: C9H15N4O8P Molecular Weight: 338.211162 Appearance: White Powder Purity: 99.21% Melting point: 213-214 °C Solubility: Soluble in DMSO (15mg/ml); or water (15mg/ml).
MOQ: 10 grams.
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HOW AICAR WORKS?
AICAR will trigger AMP activated protein kinase (AMPK), leading to glucose uptake by cells of skeletal muscle. In fact, The Howard Hughes Medical Center and Salk Institute ran a series of experiments with AICAR in the 2000’s. In these studies they found out that mice that were given AICAR could run 44% further, even without training for it. Consequently, once endurance athletes got word of this amazing compound, AICAR was being used without any regulation or fear of testing until 2011.
STACKING WITH GW-501516.
Both AICAR and GW (cardarine) are on WADA’s banned substances list, and if used together they make a potent endurance stack. One of the differences between the two is that GW is a PPAR-delta agonist, while AICAR is a PPAR-delta AMPK axis agonist.
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