Other Names: Andarine, Andarin, S-4, S-40503, GTx-007 IUPAC-Name:(2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide CAS: 401900-40-1 Formula: C19H18F3N3O6 Mol. mass: 441.357 g/mol Half life: 2.6 hours. Melting Point: 70-74 °C Storage: Room temperature Appearance: Pale yellow fine powder, odorless, acrid bitter taste. Solubility: Soluble in DMSO (85 mg/mL), Water (< 1.2 mg/mL), and Ethanol (85 mg/mL), it is also soluable in Propylene Glycol and PEG400.
General Information of Andarine (S4)
Andarine is an orally active partial agonist for androgen receptors, S-4 is effective in not only maintaining lean body mass but actually increasing it. Andarine is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects. This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH.
The usesage of S-4 / andarine.
For cutting and Strength Gains: As for the properties of S4, andarine is often compared to winstrol or anavar, while S4 provides better effects on lean muscle gains. What's more, Andarine also decreases fat while maintaining and even boosting muscle mass in a hypocaloric environment.
For Recomping: Recommended for recomping is 50-75 mg for 4 to 8 weeks. If S4 is used with a more anabolic SARM such as Ostarine, the results of recomping will be better if you’re aiming to gain muscles while losing fat.
How to use S-4 / Andarine safely?
To negating any side effects, S-4 should be dosed at 5 days on 2 off at 50mg. If you go above 50mg you will lose some night vision if the quality of S4 you got is good. S-4 has a very short half life, 2.6 hours, so it would be perfect to use as a pulse, 3 times a week 2 hours before training should give excellent strength and hardening results. Both those protocols will reduce the yellow eye, and night vision problems. Remember, a PCT (post cycle therapy) should be always carried out after using S4. If you want the effects faster, the recommended dosage for cutting is 50 mg for 6-8 weeks. It should be used every day then take 2 days off for the duration. Taking S-4 daily for the length of the cycle can lead to obvious changes by eyesight.
Running 20mg a day 6 days on 1 off for 6-10 weeks not only reduces body fat, but it has been used by me in conjunction with the only other compound I’ve ever seen reduce gyno - Letrozole (femara). Using 0.5 mg of Letrozole 3 x a week in conjunction with the S4 shows great promise in reducing steroid induced gynecomastia (gyno).
What Form of S-4 / Andarine Is Available Here?
S4 (Andarine) is offered in raw powder form and its oral liquid form, if you are interested in making oral liquid solutions or capsules for it, please don't hesitate to contact us.